Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Vertical Transmission Covid-Positive Mothers in Neonates

An outbreak of Covid-19 occurred in Wuhan, China initially in December 2019. Over the next few months, the wide spread of SARS-CoV-2 had been reported in all continents and the transmission in utero from an infected mother to fetus debating yet was observed.1,9Objectives: To determine risk of vertical transmission of corona virus in neonates of SARS COVID-2 positive mothers. Study Design: A Cross-Sectional study. Place and Duration of Study: Pediatric department of Pakistan Air Force (PAF) Hospital, Islamabad, Pakistan. The study conducted during 01-03-2020 to 31-08-2020. Methodology: After taking informed consent, Nasopharyngeal swab for PCR for SARS-CoV-2 was taken one week before delivery. Confirmed COVID positive pregnant ladies were included irrespective of symptoms of COVID-19 infection and any other medical illness. Neonates born to COVID-19 positive mothers were admitted in NICU, and Performa was filled for neonates after PCR done 24 and 48 hours respectively. Result(s): Total 14(87.5%) out of 16 COVID positive mothers were asymptomatic. 16(100%) neonates were negative for Sars- COV-2 at 24 hours and 48 hours. Conclusion(s): This study concluded with no evidence of transmission of COVID-19 from infected mothers. Copyright © 2022 Lahore Medical And Dental College. All rights reserved.

Vertical transmission of acute respiratory syndrome viruses from mother to the foetus

Since early in month of Dec-2019, the infection of Coronavirus Disease 19 has been prevalent in Wuhan City of China and ultimately virus spread to other countries. Literature survey was carried out by using different scientific sources such as PubMed, Scopus, Google scholar etc. There is a scarcity of literature of COVID-19 happening at some stage in pregnant women and possibilities of transmission vertically are may be due to COVID-19. So, there is an alarm situation as foetus may be at risk of congenital COVID-19. Up until August 28, 2020, we investigated at the risk of COVID-19 vertical transmission to the foetus of infected women using a database of published articles and government sites. Middle East Respiratory Syndrome MERS and Severe acute Respiratory syndrome SARS were related to poor obstetrical conclusion, so there was no recognized case of ‘intrauterine transmission’ of either Middle East Respiratory Syndrome-coronavirus (MERS-CoV) or severe acute Respiratory syndrome-coronavirus (SARS-CoV). © 2022 MEDIC SCIENTIFIC. All right reserved.